摘要
目的探究奥美拉唑肠溶片治疗急性肠胃炎的临床效果.方法选取本院2019年4月—2021年4月收治的112例急性肠胃炎患者,根据随机数表法分为两组.对照组56例,采用复方嗜酸乳杆菌片治疗,观察组56例,采用复方嗜酸乳杆菌片联合奥美拉唑肠溶片治疗.对两组患者的临床疗效、症状缓解时间、消化系统与肠胃功能评分,不良反应进行比较.结果临床疗效比较,观察组的98.21%高于对照组的82.14%,差异有统计学意义(P<0.05).观察组的发热、呕吐、腹泻、腹痛缓解时间均短于对照组,差异有统计学意义(P<0.05).治疗后,观察组的消化系统症状评分为(3.43±0.39)分,低于对照组的(6.84±0.74)分,差异有统计学意义(P<0.05).治疗后,观察组的肠胃功能评分为(4.62±0.96)分,高于对照组的(2.73±0.63)分,差异有统计学意义(P<0.05).不良反应比较,观察组的10.71%与对照组的8.93%比较,差异无统计学意义(P>0.05).结论采用奥美拉唑肠溶片辅助治疗急性肠胃炎能够快速缓解患者临床症状,改善其消化功能、肠胃功能,治疗效果显著,且安全性较高.
Objective To explore the clinical effect of omeprazole enteric-coated tablets in the treatment of acute gastroenteritis.Methods A total of 112 patients with acute gastroenteritis admitted to our hospital from April 2019 to April 2021 were selected and divided into two groups according to the random number table method.56 cases in the control group were treated with compound Lactobacillus acidophilus tablets,and 56 cases in the observation group were treated with compound Lactobacillus acidophilus tablets combined with omeprazole enteric-coated tablets.The clinical efficacy,symptom relief time,digestive system and gastrointestinal function scores,and adverse reactions were compared between the two groups.Results Compared with the clinical efficacy,98.21%of the observation group was higher than 82.14%of the control group,and the difference was statistically significant(P<0.05).The relief time of fever,vomiting,diarrhea,and abdominal pain in the observation group were shorter than those in the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the digestive system symptom score of the observation group was(3.43±0.39)points,which was lower than that of the control group(6.84±0.74)points,and the difference was statistically significant(P<0.05).After treatment,the gastrointestinal function score of the observation group was(4.62±0.96),which was higher than that of the control group(2.73±0.63),and the difference was statistically significant(P<0.05).In the comparison of adverse reactions,10.71%of the observation group was compared with 8.93%of the control group,and the difference was not statistically significant(P>0.05).Conclusion The use of omeprazole enteric-coated tablets for the adjuvant treatment of acute gastroenteritis can quickly relieve the clinical symptoms of patients,improve their digestive function and gastrointestinal function,with significant therapeutic effect and high safety.
作者
刘涛
战玉芳
LIU Tao;ZHAN Yufang(Department of Pharmacy,Rizhao Hospital of Traditional Chinese Medicine,Rizhao Shandong,276800,China;Department of Pharmacy,Ju County Hospital of Traditional Chinese Medicine,Rizhao City,Ju County Shandong,276518,China)
出处
《反射疗法与康复医学》
2021年第19期55-58,62,共5页
Reflexology And Rehabilitation Medicine
关键词
急性肠胃炎
奥美拉唑
临床疗效
胃肠功能
不良反应
Acute gastroenteritis
Omeprazole
Clinical efficacy
Gastrointestinal function
Adverse reactions
