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阿托伐他汀联合替罗非班在急性心肌梗死康复治疗中的应用效果探讨 被引量:2

The Eeffect of Atorvastatin Combined with Ttirofiban in the Rrehabilitation of Aacute Mmyocardial Iinfarction
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摘要 目的分析评价急性心肌梗死患者采取阿托伐他汀联合替罗非班治疗的康复疗效.方法该次将该院于2018年2月—2019年1月收治的90例急性心肌梗死患者作为研究对象,进一步以随机数字抽样法分为两组,各45例;其中,对照组患者采取常规方法治疗,观察组在此基础上,重点使用阿托伐他汀联合替罗非班治疗,进一步比较两组临床康复治疗效果.结果(1)在康复疗效对比方面,观察组显效31例(68.89%)、有效12例(26.67%)、无效2例(4.44%),对照组显效15例(33.33%)、有效19例(42.22%)、11例(24.44%),在康复治疗总有效率上,观察组为95.56%,与对照组的75.56%比较明显更高,两组之间的数据差异有统计学意义(χ^(2)=10.261,P<0.05).(2)两组心血管风险事件发生情况方面,观察组心绞痛1例(2.22%)、再发梗死1例(2.22%)、严重心力衰竭0例(0.00%)、心源性死亡0例(0.00%),对照组心绞痛5例(11.11%)、再发梗死4例(8.89%)、严重心力衰竭1例(2.22%)、心源性死亡1例(2.22%),心血管风险事件总发生率观察组为4.44%,明显低于对照组的24.44%(χ^(2)=10.287,P<0.05).(3)观察组用药不良反应总发生率为2.22%,与对照组的4.44%对比差异无统计学意义(χ^(2)=1.783,P>0.05).结论在临床中针对急性心肌梗死患者,采取阿托伐他汀联合替罗非班治疗的康复疗效显著,心血管风险事件发生率及用药不良反应发生率均偏低,安全高效. Objective To evaluate the rehabilitation effect of aAtorvastatin cCombined with tirofiban in patients with acute myocardial infarction.Methods Tthis time,90 patients with acute myocardial infarction admitted to the hospital from February 2018 to January 2019 were taken as the research objects,and further divided into two groups with by random digital sampling method,45 cases in each group.Among them,tThe patients in the control group were treated with conventional methods.On this basis,the observation group focused on the treatment of aAtorvastatin cCombined with tirofiban,and further compared the clinical rehabilitation effect of the two groups.Results 1.In terms of the comparison of rehabilitation efficacyeffect,the observation group showed significant effective 31(68.89%),effective 12(26.67%),ineffective 2(4.44%),the control group showed significant effective 15(33.33%),effective 19(42.22%),ineffective 11(24.44%).In terms of the total effective rate of rehabilitation treatment,the observation group was 95.56%,which was significantly higher than the control group's 75.56%.There was statistically significant difference between the two groups(χ^(2)=10.261,P<0.05).2.In terms of cardiovascular risk events,angina 1(2.22%),reinfarction 1(2.22%),severe heart failure 0(0.00%),cardiac death 0(0.00%)in the observation group,angina 5(11.11%),reinfarction 4(8.89%),severe heart failure 1(2.22%),cardiac death 1(2.22%)in the control group,The total incidence of cardiovascular risk events in the observation group was 4.44%,significantly lower than that in the control group 24.44%(χ^(2)=10.287,P<0.05).3.The total incidence of adverse drug reactions in the observation group was 2.22%,which had no statistically significant difference compared with 4.44%in the control group(χ^(2)=1.783,P>0.05).Conclusion Iin the clinical treatment of acute myocardial infarction patients,aAtorvastatin cCombined with tirofiban has significant rehabilitation effect,the incidence of cardiovascular risk events and adverse drug reactions are low,safe and efficient.
作者 李锋 LI Feng(Linyi City Lanshan District People's Hospital,Linyi Shandong,276000,China)
出处 《反射疗法与康复医学》 2020年第12期82-84,共3页 Reflexology And Rehabilitation Medicine
关键词 阿托伐他汀 替罗非班 急性心肌梗死 康复治疗 应用效果 Aatorvastatin Ttirofiban Aacute myocardial infarction Rrehabilitation treatment Aapplication effect
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