摘要
The chronic infection of hepatitis B virus(HBV)is the major cause of hepatocellular carcinoma(HCC)globally[1].In Eastern China,chronic HBV infection contributes to 87.5%of HCC whereas chronic hepatitis C virus(HCV)infection contributes to 1.7%[2].The mortality of HCC has increased in Europe and America over recent decades[3].Although the infection of HCV is the leading cause of HCC in most European and American countries,the contribution of HBV is increasing possibly due to immigration[3].
基金
This work was supported by grant(2015CB554006)from the National Key Basic Research Program of China(GC)