摘要
目的:研究肾性甲状腺功能亢进患者甲状旁腺切除术后全段甲状旁腺激素(iPTH)检测及其对血管钙化的影响.方法:回顾性分析我院2016年4月~2018年3月期间收治的79例肾性甲状腺功能亢进患者的诊疗情况,分析所有患者进行甲状旁腺切除术前后的iPTH变化及血管钙化情况.结果:手术半月后及手术3个月后患者血清中iPTH、钙、磷浓度均明显低于手术前,差异有统计学意义.手术3个月后,患者冠状动脉钙化总评分显著低于手术前,差异有统计学意义;手术3个月后患者冠状动脉钙化率(91.14%)明显低于手术前(98.73%),差异有统计学意义.结论:对肾性甲状腺功能亢进患者实施甲状旁腺切除术,能够显著降低患者的血清iPTH浓度,同时减轻患者的冠状动脉钙化程度,值得在临床上广泛应用.
Objective To study detection of Intact Parathyroid Honnone(iPTH)and its effect on vascular calcification af-ter parathyroidectomy in patients with renal hyperthyroidism.Methods 79 cases with renal parathyroidectomy in this hospital from April 2016 to March 2018 were selected as objectives.The changes of iPTH and vascular calcification before and after parathyroidectomy were analyzed in all patients.Results After 3 months of operation,the concentrations of iPTH,calcium and phosphorus in serum were markedly lower than those before operation,and the difference was notably significant.After 3 months of operation,the total coronary artery calcification score was visibly lower than that before the operation,The difference was statistically significant.The coronary artery calcification rate(91.14%)after 3 months was prominently lower than that before operation(98.73%),and the difference was statistically significant.Conclusion Parathyroidectomy for patients with renal hyperthyroidism can distinctly reduce the serum concentration of iPTH and reduce the degree of coronary artery calcification in sufferers,which is worthy of clinical application.
作者
陈静
韦传娃
范平明
Chen Jing;Wei Chuan-wa;Fan Ping-ming(The First Affiliated Hospital of Hainan Medical University,Haikou 570102,China)
出处
《湖南师范大学学报（医学版）》
2019年第4期65-68,共4页
Journal of Hunan Normal University(Medical Sciences)
