摘要
目的研究降钙素原及白介素-6检测在早期新生儿感染中的临床意义。方法选取45例感染患儿作为观察组,另选取同期的40例非感染新生儿作为对照组。对两组新生儿均进行降钙素原及白介素-6检测,对比检测结果。结果感染观察组的降钙素原及白介素-6水平分别为(7.98±3.51)ng/ml、(195.10±21.87)pg/ml,明显高于对照组(<0.05);二者联合应用时的敏感度和特异度也高于单独应用。结论降钙素原与白介素-6联合检测对于早期判断新生儿感染具有重要临床意义。
Objective To study the clinical significance of procalcitonin and interleukin-6 detection in early neonatal infection.Methods A total of 45 neonates with bacterial infection were selected as observation group.Another 38 neonates without infection were taken as control group.Procalcitonin and interleukin-6 were detected and results were compared.Results The infection group had procalcitonin and interleukin-6 levels as(7.98±3.51)ng/ml and(25.73±4.68)mg/L,which were all obviously higher than the control group(<0.05);That PCT and IL-6 used together could increase the sensitivity and specificity.Conclusion Combination of Procalcitonin and interleukin-6 detection is of important clinical significance for judgment of neonatal infection.
作者
吴玉霞
WU Yu-xia(Department of Neonatology,Jinghai District Hospital of Medical University of Tianjin,Tianjin 301600,China)
