摘要
目的:观察患者的高血压依那普利叶酸治疗效果与动态血压监测。方法对我院收治的89例H型高血压患者随机分为对照组(44例)和观察组(45例),给予依那普利和依那普利叶酸治疗,连续8w的双盲治疗,动态血压监测在白天,晚上,24h平均值均在8w的治疗,分析和降低血压和血浆同型半胱氨酸的影响,并观察治疗8w后的心脏和血压昼夜节律。结果①治疗组比对照组在血压监测中要低(P<0.01);②治疗组血浆同型半胱氨酸水平(P<0.01),总有效率高②对照组(P<001)。结论 H型高血压患者依那普利叶酸治疗的临床效果,降低了血压和血浆HCY水平。
Objective Ef ect of ambulatory blood pressure monitoring observation of enalapril folic acid treatment of H type hypertension.Methods 89 patients of H admit ed to our hospital hypertension control group(44 cases)and study group(45 cases),continuous double-blind treatment for 8 W,dynamic blood pressure monitoring during the day,night,24 h mean mean mean at after 8 W treatment respectively,and the analysis of lowering blood pressure and plasma homocysteine(Hcy)ef ect.Results①The dynamic blood pressure study group after treatment were superior to the control group(<0.01);②The levels of plasma Hcy study group after treatment than in the control group(<0.01),total ef iciency is higher than that of the control group(<0.01);study group of systolic and diastolic pressure fluctuations are less,the abnormal rhythm in patients with fewer than the control group(<0.05).Conclusion The clinical ef ect of folic acid type H in hypertension treated with enalapril treatment,reduce blood pressure and plasma HCY level.
作者
谢志红
XIE Zhi-hong(Department of Cardiovascular Medicine,Ganzhou People's Hospital,Ganzhou 341000,Jiangxi,China)
关键词
H型高血压
依那普利叶酸
血压监测
H type hypertension
Enalapril folic acid
Blood pressure monitoring
