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脓毒症患者血浆N末端脑钠肽前体水平与预后相关性研究 被引量:1

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摘要 目的:探讨脓毒症患者血浆N末端脑钠肽前体(NT-proBNP)水平与患者预后的相关性。方法50例脓毒症患者为研究对象,检测血浆NT-proBNP、乳酸、C反应蛋白(CRP)水平,评估入院24h急性生理和慢性健康状态评分Ⅱ(APACHEⅡ)评分,比较不同病变程度及不同预后患者各指标差异,并比较各指标间相关性。结果严重脓毒症组、脓毒症休克组患者血浆NT-proBNP、乳酸、APACHEI、CRP均明显高于一般脓毒症组(<0.05);死亡组血浆各指标值均高于存活组(<0.05);NT-proBNP水平与乳酸、APACHE I 评分、CRP间呈正相关,相关系数分别为0.356,0.525,0.537(<0.05)。结论血浆NT-proBNP与患者预后密切相关,检测NT-proBNP水平有助于判断患者预后。
出处 《医学信息(医学与计算机应用)》 2014年第30期85-86,共2页 Medical Information
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