摘要
目的:探讨中药注射剂致过敏反应的规律和特点,为临床合理用药提供依据。方法采用回顾性分析的方法,收集我院2011~2013年中药注射剂不良反应(ADR)上报的报表,共89例,对其进行汇总、分析。结果过敏反应发生的年龄分布集中在41~50岁,引起过敏反应的中药注射剂共9个品种,发生过敏反应频率最高的药物是参麦注射液。3例严重过敏反应均表现为过敏性休克。结论需严格掌握中药注射剂的适应症和禁忌症,过敏体质患者避免使用,滴注前30 min内应严密监视患者表现,并采取相应的防护措施。
Objective To analyze the rules and characteristics of the occurrence of the al ergic reactions caused by traditional Chinese medicine injections so as to provide reference for clinical rational drug use.Methods A total of 89 adverse reaction(ADR)reports associated with traditional Chinese medicine injections received in 2011~2013 were retrospectively analyzed.Results Age distribution of allergic reaction was concentrated in 41~50 years old.The traditional Chinese medicine injection causing al ergic reactions were 37 varieties and the highest frequency of al ergic reactions was shenmai injection.3cases of severe al ergic reactions were manifested as anaphylactic shock.Conclusion Grasp the indications and contraindications of traditional Chinese medicine injections.Patients with al ergies should avoid to use.Performance of patients should be closely monitored within 30 min after infusion.Medical staf s should take appopriate protective measures.
作者
李云
LI Yun(Department of Pharmacy,Shengli Hospital,Qilu Petrochemical Hospital Group,Zibo 255434,Shandong,China)
关键词
中药注射剂
过敏反应
Ttraditional Chinese medicine injection
Aal ergic reactions
