摘要
目的:探讨连蛭保肾汤联合卡托普利治疗高血压病早期肾损害的临床效果及价值。方法选取2011年7月~2014年3月,在我院接受治疗的高血压病早期肾损害患者117例,根据患者具体情况分为观察组(卡托普利治疗)65例和对照组(连蛭保肾汤联合卡托普利治疗)52例,观察并比较两组患者的24h尿总蛋白定量、β2-MG、尿mALB均值。结果两组患者治疗前24h尿总蛋白定量、β2-MG、尿mALB均值无明显差异;治疗后两组患者24h尿总蛋白定量、β2-MG、尿mALB均值均明显下降,下降幅度观察组明显高于对照组,P<0.05,有统计学意义;两组患者均无严重不良反应事件发生。结论连蛭保肾汤联合卡托普利治疗高血压病早期肾损害疗效显著,具有临床应用价值。
Objective To investigate the clinical effect and value of even for protecting kidney Combined with captopril in treatment of renal damage in early stage of hypertension.Methods From 2011 July 2014 March treated in our hospital in early renal damage of hypertension patients with 117 cases,according to the specific situation of patients were divided into observation group(captopril)in 65 cases and the control group(even for protecting kidney Combined with captopril in treatment 52 cases),was observed and 24 hour urinary total protein quantitative,comparison of two patients with aβ2-MG,urine mALB value.Results The two groups of patients before treatment and 24 hour urinary protein quantitative,β2-MG,urine mALB mean no significant dif erence between the two groups after treatment;24 hour urinary protein quantitative,β2-MG,urine mALB value decreased significantly,decreased the observation group was significantly higher than that in control group,P<0.05,control significance;the patients in two groups were no serious adverse events.Conclusion Even for protecting kidney Combined with captopril in treatment of renal damage in early stage of hypertension with obvious curative ef ect,low incidence of adverse reactions,has the value of clinical application.
作者
肖漫江
XIAO Man-jiang(The Second Hospital of Zhuzhou City,Zhuzhou 412005,Hunan,China)
关键词
连蛭保肾
卡托普利
高血压病早期肾损害
临床效果
Even for protecting kidney
Captopril
Renal damage in early stage of hypertension
Clinical ef ect
