摘要
目的观察尼可刹米治疗顽固性呃逆的临床疗效。方法对顽固性呃逆患者给予尼可刹米肌注,并与胃复安肌注组进行比较,观察两组治疗的临床疗效及不良反应。结果尼可刹米治疗组中,38例治疗有效,6例好转,总有效率达91.7豫。胃复安治疗组中,7例治疗有效,10例好转,总有效率达68豫。两组比较<0.05,差异有显著性。结论肌注尼可刹米治疗顽固性呃逆是一种快速、有效、安全的方法。
Objective The aim of this study was to investigate the treatment ef icacy of intractable hiccup(IH)by nikethamide.Methods Compared the treatment ef icacy and adverse reaction of nikethamide or metoclopramide intramuscular injection for intractable hiccup.Results In nikethamide group,38 cases were ef ective,and 6 cases were improved,the total ef icacy were 91.7%.In metoclopramide group,7 cases were ef ective,and 10 cases were improved,the total ef icacy were 68%.There were significant dif erences in two group(<0.05).Conclusion Nikethamide intramuscular injection is a rapid,ef ective and safety method for treatment of intractable hiccup.
作者
吴海东
黄勇
吴满辉
WU Hai-dong;HUANG Yong;WU Man-hui(Department of Emergency,Sun-Yat-Sen Memorial Hospital,Sun-Yat-Sen University,Institute of Cardiopulmonary Cerebral Resuscitation,Sun-Yat-Sen University,Guangzhou 510120,Guangdong,China;Leping Town Centre Hospital of Sanshui,Foshan 528000,Guangdong,China)
基金
广东省科技计划社会发展项目(编号:2012B031800084).
关键词
顽固性呃逆
治疗
尼可刹米
Intractable hiccup
Treatment
Nikethamide