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抗环瓜氨酸肽抗体与类风湿因子检测对类风湿关节炎诊断价值的分析

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摘要 目的研究抗环瓜氨酸肽(抗CCP抗体)和类风湿因子(RF)的检测在类风湿关节炎(RA)诊疗中的临床价值。方法分别用酶联免疫吸附试验( ELISA)、BN-II特定蛋白分析仪同时检测RA组110例,其他风湿性疾病组65例,健康对照组35例患者血清抗CCP抗体和RF。结果抗CCP抗体和RF对RA诊断的灵敏度分别为72.7豫、82.7豫,抗CCP抗体与RF灵敏度之间差异无显著性;2种抗体对RA诊断的特异度分别为95豫、77豫,抗CCP抗体的特异性比RF高。结论检测抗CCP抗体有助于提高类风湿关节炎的诊断率。
出处 《医学信息(医学与计算机应用)》 2014年第19期337-337,共1页 Medical Information
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