摘要
目的:探讨冻干重组人脑利钠太治疗顽固性心力衰竭的临床效果。方法选取新疆自治区人民医院心内科 CCU室2011年1月~2012年12月收治的56例顽固性心力衰竭患者,随机分为对照组及治疗组,每组28例,对照组采用常规传统心力衰竭治疗,治疗组在对照组的基础上应用重组人脑钠肽,比较两组患者的临床治疗效果。结果在总有效率及BNP及LVEF的改善上治疗组改善均优于对照组,组间差异有统计学意义(P<0.05),两组在治疗期间均无明显不良反应。结论重组人脑钠肽对于顽固性心力衰竭疗效由于传统疗法,不良反应少,适合临床使用。
Objective To study lyophilized recombinant human brain natriuretic clinical ef ect to refractory heart failure.Methods Xinjiang Autonomous Region People's Hospital CCU room in January 2011-2012 December 56 treated patients with refractory heart failure were randomly divided into a control group and the treatment group,28 cases in the control group using conventional traditional ef ort failure treatment group recombinant human brain natriuretic peptide in the control group on the basis of the clinical treatment of patients were compared.Results The total ef iciency improvement of LVEF and BNP and improve treatment groups than the control group between the two groups was statistical y significant(P<0.05)dif erences between the two groups during the treatment had no significant adverse reactions.Conclusion The recombinant human brain natriuretic peptide for refractory heart failure due to the traditional therapy ef icacy,fewer side ef ects,suitable for clinical use.
作者
古孜丽
高方明
刘永国
GU Zi-li;GAO Fang-ming;LIU Yong-guo(Department of Cardiology,The Xinjiang Uygur Autonomous Region people's Hospital,Urumqi 830000,Xinjiang,China)
关键词
利钠肽
难治性心力衰竭
脑钠肽
疗效
Natriuretic peptide
Refractory heart failure
Brain natriuretic peptide
Ef icacy
