摘要
To the Editor:Major depressive disorder(MDD)affects over 300 million individuals globally,impairing daily life and leading to severe cases of suicide.Child maltreatment(CM),encompassing various types of mistreatment to children under 18 years,is a predisposing factor for MDD,with approximately 46%of MDD patients having experienced CM.[1]Understanding the biological mechanisms linking CM to MDD may reveal prevention and management strategies.
基金
funded by the Science and Technology Innovation 2030 Major Projects(No.2022ZD0211600)
the National Natural Science Foundation of China(Nos.82071204 and 82271574 to XCM,and 82201237 to CCH)
the Key Project of Jiangsu Commission of Health(No.ZDB2020008).