摘要
在癌症的发生发展中,肿瘤免疫起着至关重要的作用,免疫治疗已成为癌症治疗的里程碑。外泌体环状RNA具有成为无创性生物标志物的潜力,并且多项研究表明其参与肿瘤免疫和癌症免疫治疗耐药性。在这篇综述中,我们总结了外泌体环状RNA在调节肿瘤免疫、预测免疫治疗疗效方面的作用。外泌体环状RNA在癌症临床治疗中具有巨大前景。
Tumor immunity plays a significant role in the occurrence and development of cancer.Immunotherapy has become a milestone in cancer treatment.Exosomal circRNA have the potential to be noninvasive biomarkers.Several studies showed that exosomal circRNA involved in tumor immunity and cancer immunotherapy resistance.In this review,we summarized the role of exosomal circRNA in regulating tumor immunity and predicting immunotherapy efficacy.Exosomal circRNA has great prospects in the clinical treatment of cancer.
作者
张可
闫琳琳
王鹏飞
章秀林
赵帆
胡守奎
Zhang Ke;Yan Linlin;Wang Pengfei;Zhang Xiulin;Zhao Fan;Hu Shoukui(Department of Clinical Laboratory,Peking University Shougang Hospital,Beijing 100144,China)
出处
《中华临床医师杂志（电子版）》
CAS
北大核心
2023年第10期1102-1108,共7页
Chinese Journal of Clinicians(Electronic Edition)
基金
首颐医疗科技发展基金(SGYYQ202102)
