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实施加速康复外科管理对卵巢癌分期手术老年患者术后早期恢复的影响

Effect of enhanced recovery after surgery on early recovery of elderly patients undergoing ovarian cancer staging surgery
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摘要 目的探讨实施加速康复外科(ERAS)管理对卵巢癌分期手术老年患者术后早期恢复的影响。方法选取2018年3月至2021年3月于广东省韶关市粤北人民医院治疗的老年卵巢癌患者82例,均行卵巢癌分期手术治疗。观察组采取ERAS管理,对照组采取常规围术期管理。记录2组患者首次排气时间、下床活动时间、留置尿管时间和住院时间。比较2组患者术前1 d、术后12 h和术后24 h患者简易精神状态量表(MMSE)评分和应激指标[C反应蛋白(CRP)和皮质醇(Cor)]变化,及术后12 h和术后24 h国际通用数字分级法(NRS)评分。结果观察组首次排气时间、下床活动时间、留置尿管时间和住院时间短于对照组(P均<0.05)。2组术后12 h和术后24 h患者MMSE评分低于术前1 d(P均<0.05);观察组术后12 h和术后24 h患者MMSE评分高于对照组(P均<0.05)。2组术后12 h和术后24 h血清CRP和Cor水平高于术前1 d(P均<0.05);观察组术后12 h和术后24 h患者血清CRP和Cor水平低于对照组(P均<0.05)。观察组术后12 h和术后24 h患者NRS评分低于对照组(P均<0.05)。结论实施ERAS管理对卵巢癌分期手术患者效果良好,可促进患者术后早期恢复,减轻应激反应及疼痛。 ObjectiveTo explore the impact of enhanced recovery after surgery(ERAS)management on the early recovery of elderly patients undergoing ovarian cancer staging surgery.MethodsWe selected 82 elderly patients who underwent staging surgery for ovarian cancer at Yuebei People's Hospital,Shaoguan City,Guangdong Province from March 2018 to March 2021 and divided them into an observation group and a control group.The observation group was managed by ERAS,and the control group was managed by routine perioperative management.The time to first exhaust,time to ambulation,catheter indwelling time,and hospital stay were recorded for the two groups of patients;mini-mental state examination(MMSE)scores and stress indicators[C-reactive protein(CRP)and cortisol(Cor)]were compared at 1 d preoperatively and 12 h and 24 h postoperatively,and international numerical rating scale(NRS)scores were compared at 12 h and 24 h postoperatively.ResultsThe time to first exhaust,time to ambulation,catheter indwelling time,and hospital stay were significantly shorter in the observation group than in the control group(P<0.05 each).The MMSE scores at 12 h and 24 h postoperatively were significantly lower than those at 1 d preoperatively in both groups(P<0.05 each);these scores were significantly higher in the observation group than in the control group(P<0.05 each).Serum CRP and Cor levels at 12 h and 24 h postoperatively were significantly higher than those at 1 d preoperatively in both groups(P<0.05 each);these scores were significantly lower in the observation group than in the control group(P<0.05 each).The NRS scores at 12 h and 24 h postoperatively were significantly lower in the observation group than in the control group(P<0.05 each).ConclusionERAS management has a good effect in patients undergoing ovarian cancer staging surgery,which can promote early postoperative recovery and reduce stress reaction and pain.
作者 谢文强 张强 陈文 李长科 魏兵华 唐盈 Xie Wenqiang;Zhang Qiang;Chen Wen;Li Changke;Wei Binghua;Tang Ying(Department of Anesthesiology,Yuebei People's Hospital,Shaoguan 512025,China)
出处 《中华临床医师杂志(电子版)》 CAS 北大核心 2021年第12期999-1002,共4页 Chinese Journal of Clinicians(Electronic Edition)
基金 韶关市卫生计生科研项目(Y19025)
关键词 加速康复外科管理 卵巢癌分期手术 老年人 术后早期恢复 Enhanced recovery after surgery manage Ovarian cancer staging surgery Elderly Early postoperative recovery
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