摘要
目的探讨小鼠受移动通信微波辐射后学习记忆能力的变化。方法将青(5月龄)、老年(10月龄)清洁级雄性昆明种小鼠随机分为青年对照组、青年辐射组、老年对照组、老年辐射组,每组10只。辐射组小鼠安置在移动电话微波基站(电场强度为3V/m)下,每天另采用2只通话中的移动电话加强微波辐射5h,连续50d。对照组安置在无辐射处(电场强度为0V/m)。通过Morris水迷宫比较测试各组小鼠学习、记忆能力(寻找平台所需时间:潜伏期),以分光光度法测定各组小鼠海马与颞叶区乙酰胆碱酯酶(AchE)活力。结果随着训练次数的增多,各组小鼠的潜伏期呈下降趋势,差异无统计学意义(P>0.05)。与青年对照组比较,老年对照组小鼠潜伏期有延长趋势。青年对照组和老年辐射组小鼠颞叶和海马中AchE活力均低于老年对照组,差异有统计学意义(P<0.05)。青年辐射组小鼠海马中AchE活力高于青年对照组,差异有统计学意义(P<0.05)。结论移动通信微波辐射对老年小鼠学习记忆能力可能影响不大或有正面影响,但对正常的青年小鼠可能有一定的负面影响。
Objective To study the effects of mobile telephone microwave radiation on learning and memory of young and senile mice. Methods The young(5 months old) and senile(10 months old) male Kunming mice were randomly divided into 2 groups respectively, the control and exposed. The young and senile mice were settled in the environment of the mobile telephone signal shoots station (3 V/m) and exposed to the mobile telephone conversation radiation with two mobile telephones for 5 h/d for 50 consecutive days. The control group was in the environment without microwave radiation (0 V/m). The capability of learning and memory of each group were determined by Morris maze test(the time of finding the flat roof:the latency), the activity of acetylcholinesterase (AchE) in the hippocampus and temporal lobe were measured by spectrophotometry. Results With the increase of training time, no significant decrease of the latency was seen in each group. Compared with the senile control group, the activity of AchE in the hippocampus and temporal lobe of the young control group and the senile radiation group were lower(P<0.05). Compared with the young control group, the activity of AchE in the hippocampus of the young radiation group was higher(P<0.05). Conclusion Mobile telephone microwave radiation may have little impact or have a positive impact on the learning and memory ability in the senile mice, but it may have an adverse effect in the young mice.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2007年第11期905-907,共3页
Journal of Environment and Health
基金
上海市教委中医人才高地建设基金资助项目
