摘要
目的:探讨心力衰竭患者血浆BNP浓度对心功能的评价作用。方法:选择我院门诊和住院确诊的慢性心力衰竭患者59例,正常对照组31例。用博适Triage干式快速定量心肌梗死心力衰竭诊断仪(美国Biosite公司)检测受试者血浆BNP浓度,所得结果进行统计学检验,分析慢性心力衰竭患者血浆BNP浓度与心力衰竭严重程度的相关性。结果:慢性心力衰竭患者血浆BNP浓度较对照组显著增高,且随心力衰竭程度的加重而明显增加(P<0.01)。结论:血浆BNP水平可以客观准确地评价心功能,可作为一项临床诊断心力衰竭的实验室指标。
Objective:To determine the effects of plasma B-type natriuretic peptide(BNP)on cardiac function in patients with heart failure.Methods:We measured plasma BNP of whole venous blood with Triage Meter Plus by BIOSITE in 59 heart failure patients and 31 normal controls.The results were analyzed for the correlation between BNP concentration and NYHA functional class.Results:The plasma BNP concentration in heart failure patients was significantly higher than those in the normal controls and increased with the increased severity of heart failure(P<0.01).Conclusions:Plasma BNP level is a useful index for the evaluation of cardiac function.In heart failure patients,the BNP was gradually and significantly increased with the worsened NYHA functional class.
出处
《青海医药杂志》
2007年第11期1-2,共2页
Qinghai Medical Journal
基金
青海省科技厅自然科学基金项目(编号2006-N-149)部分研究内容
