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超声造影与彩色多普勒超声诊断肝实质性肿块对照研究

Comparison between contrast enhanced ultrasound and colour Doppler ultrasound differential diagnosis of hepatic tumors
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摘要 目的比较彩色多普勒超声和实时超声造影对肝实质性肿块的诊断价值。方法应用彩色多普勒超声及超声造影技术对常规二维超声难以定性的27例共31个肝实质性肿块进行检查,结果与手术及病理结果相对照。结果31个肿块中原发性肝细胞性肝癌24个,肝血管瘤3个,肝脏局灶性结节增生3个,肝孤立性坏死结节1个。彩色多普勒超声在肿块内部或肿块周边能检测到动脉血流频谱者共19例21个肿块;超声造影除一例肝孤立性坏死结节外,其余30个病灶均在不同时相出现不同程度强化现象。如以动脉相呈高回声而门脉相及延迟相呈低回声为恶性肿块的诊断标准,则超声造影对肝癌诊断的准确率为91.67%;如以肿块内部检测到动脉样血流频谱为诊断恶性肿块的诊断标准,则彩色多谱勒超声诊断肝癌的准确率为75%。超声造影诊断肝实质性肿块准确率为93.54%,彩色多普勒超声诊断肝实质性肿块准确率为64.52%。二者差别有统计学意义(P<0.05)。结论实时超声造影显著提高肝内实质性肿块的诊断准确性,对肝脏实质性肿块良、恶性的诊断及鉴别诊断具有重要价值。 Objective To compare contrast enhanced ultrasound with colour doppler ultrasound in differential diagnosis of liver tumors.Methods Twenty-seven patients with 31 hepatic solid lesions underwent contrast enhanced ultrasound and colour Doppler ultrasound examinations.Results All lesions were confirmed by pathologic study,including 24 hepatocellular carcinoma,3 hepatic hemangiomas,3 focal nodular hyperplasia of liver,and 1 solitary necrotic nodule of liver.Doppler ultrasound was capable of detecting the arterial blood flow in 21 hepatic solid lesions.All hepatic solid lesions except one solitary necrotic nodule were variously enhanced in different phases after injection of sonoven.With the hepatic lesions showing early enhancement in arterial phase and rapid wash-out during portal and delayed phases on contrast enhanced ultrasonogram and those showing arterial blood flow in the lesions or around the lesions on colour Doppler imaging diagnosed as hepatic malignant tumors,The dignestic accuracies of contrast ultrasound and colour Doppler ultrasound were 91.67% and 75%,respectively,while those in diagnosis of parenchymatous liver tumors were 93.54% and 64.52%,respectively(P<0.05).Conclusions Real time contrast ultrasound signiticantly improves the accuracy in diagnosis of hepatic malignnt tumors,compared with the colour doppler ultrasound;it is a useful technique in the differential diagnosis of hepatic tumors.
出处 《武警医学》 CAS 2007年第3期173-176,共4页 Medical Journal of the Chinese People's Armed Police Force
基金 安徽省临床医学重大应用技术项目(2005Z042)
关键词 超声检查 造影剂 肝肿瘤 Ultrasound Contrast agent Liver tumor
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参考文献8

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