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三种方法检测孕妇血清IgG抗A(B)效价的结果比较 被引量:6

Comparing the Results of the Determination of Anti-A(B) IgG Titers with Three Assays in the Pregnant Women
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摘要 目的:比较经典法、改良法和微柱凝胶法抗人球蛋白试验检测孕妇血清中IgG抗A(B)效价的差异。方法:用经典法、改良法和微柱凝胶法分别检测136例孕妇血清中IgG抗A(B)效价,计算其阳性率,再以经典法为标准计算改良法和微柱凝胶法的特异性和敏感性。结果:经典法、改良法和微柱凝胶法检测孕妇血清中IgG抗A效价的阳性率分别为22.8%、25.0%和33.8%,IgG抗B效价的阳性率分别为19.1%、20.5%和31.6%。与经典法比较,改良法敏感性为98.1%,特异性为96.3%;微柱凝胶法敏感性为100%,特异性为63.4%。经统计学比较,,改良法和经典法的阳性率无统计学意义(P>0.05),而微柱凝胶法阳性率明显高于经典法(P<0.01)。结论:改良法和经典法检测孕妇血清中IgG抗A(B)效价的结果具有良好的一致性,而微柱凝胶法阳性率明显高于经典法,需重新设定临床意义决定值。 Objective To study comparatively the different of micro-column gel(MCG),improvement and classic Coombs,test in the determination of anti-A(B)IgG titers of the pregnant women.Methods Sera were obtained from 136 pregnant women,Anti-A(B)IgG titers were determined respectively by the MCG,improvement and classic Coombs,test.The positive rate,sensitivity and specificity of three assays were evaluated.Results The positive rate of anti-A IgG titers with MCG,improvement and classic Coombs,test were separately 33.8%、...
出处 《实用医技杂志》 2008年第5期555-557,共3页 Journal of Practical Medical Techniques
关键词 孕妇 IGG抗A(B)效价 抗人球蛋白试验 经典 改良 微柱凝胶 Pregnant women Anti-A(B)IgG titers Coombs test Classic Improvement Micro-column gel
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