摘要
目的比较ARB类与ACEI类减少Ⅳ期糖尿病肾病尿蛋白的疗效。方法100例糖尿病肾病Ⅳ期患者随机分为2组,分别应用科素亚、洛汀新治疗8周,检测并对比实验前后24 h尿蛋白总量。结果科素亚与洛汀新对降低Ⅳ期糖尿病肾病患者尿蛋白量的效果相似。结论ARB与ACEI类药物减少Ⅳ期糖尿病肾病患者尿蛋白量的疗效无差异。
Objective To compare the therapeutic effects of angiotensinⅡ-receptor blockers(ARB) and angiotensin-converting enzyme inhibitors(ACEI) on reducing the level of albuminuria in diatetic nephropathy phase Ⅳ.Methods One hundred patients with diabetic nephropathy phase Ⅳ were divided into two groups randomly and were treated with Losartan Potassium tablets or Lotensin for eight weeks,and the levels of albuminuria for 24 hours were measured both before and after eight weeks treatment.Results The curative effects of Losartan Potassium tablets and Lotensin on reducing the level of albuminuria in diabetic nephropathy phase Ⅳ were similar.Conclusion There is no difference in the curative effects of ARB and ACEI on reducing the level of albuminuria in diabetic nephropathy phase Ⅳ.
出处
《实用药物与临床》
CAS
2006年第6期348-349,共2页
Practical Pharmacy and Clinical Remedies
关键词
科素亚
洛汀新
糖尿病肾病Ⅳ期
Losartan Potassium tablets
Lotensin
Diabetic nephropathy phase Ⅳ
