摘要
采自贵州兴义的尾叶远志(Polygala caudataRehd.et Wils.)根,经乙醇提取,再用不同溶剂萃取和柱层析分离,得到了12个不同的组分。用比色法研究了各组分还原三价铁离子及清除脂性自由基DPPH能力,采用化学发光法观察各组分清除羟自由基和超氧阴离子的活性。研究发现,尾叶远志各组分均有一定的清除自由基作用,并且其活性成分可能主要集中在PC-BuOH组分。
Twelve fractions were isolated from the roots of Polygala caudata Rehd.et Wils..The scavenging activity to DPPH,superoxide anions and hydroxy radical,and reducing effect on Fe^3+ in vitro were studied.All fractions exhibited antioxidative effect in vitro and the antioxidative effect of n-butanol fraction of ethanol extract was superior to those of other fractions.It was suggested that traditional application of Polygala caudata Rehd.et Wils.in China may be related to its antioxidative activity.
出处
《天然产物研究与开发》
CAS
CSCD
2006年第5期717-720,共4页
Natural Product Research and Development
基金
国家自然科学基金项目(3001161940)
国家"十五"重大科技专项"创新药物和中药现代化"项目(2004AA2Z3782)
关键词
尾叶远志
抗氧化
自由基
Polygala caudata Rehd.et Wils.
antioxidant
free radical
