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FT_4/FT_3与血肌酐作为甲状腺毒症病因鉴别指标的可行性研究 被引量:4

The feasibility study on ratio of serum free thyroxine to free triiothyronine(FT_4/FT_3) and serum creatinine as parameters for differentiation of thyrotoxicosis
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摘要 目的:探讨FT_4/FT_3鉴别亚急性甲状腺炎与Graves病的临床价值。方法:选择亚急性甲状腺炎30例与Graves病30例患者,通过对FT_4/FT_3、血肌酐、血沉、甲状腺摄碘率等进行分析,来获得区别亚急性甲状腺炎与Graves病的有效指标及相应切点值。结果:除FT_4在两组间差异无统计学意义外(P>0.05),FT_3、FT_4/FT_3、血肌酐、血沉、甲状腺摄碘率两组间差异均有统计学意义(P<0.05)。以FT_4/FT_3值≥2.8作为区别亚急性甲状腺炎与Graves病的切点时,灵敏度为83.30%、特异度为76.67%。以SCr≥60μmol/L来诊断亚急性甲状腺炎与Graves病时,灵敏度为63.33%、特异度为73.33%。结论:FT_4/FT_3是区别亚急性甲状腺炎与Graves病的有效指标,对于甲状腺毒症患者当FT_4/FT_3≥2.8时,要考虑亚急性甲状腺炎可能。血肌酐对于鉴别两者也有一定的价值。 Objective:To make a distinction between subacute thyroiditis and Graves disease with some simple and pratical parameters.Methods:30 patients with subacute thyroiditis and 30 with Graves disease were studied.Through analysis of FT_4/ FT_3 ratio,serum creatinine(SCr),erythrocyte sedimentation rate(ESR) and radioactive iodine uptake (RAIU),the valuable pa- rameters and the relevant cutoff values to differentiate subacute thyroiditis from Graves disease were got.Results:FT_3,FT_4/ FT_3 ratio,SCr,ESR and RAIU...
出处 《南通大学学报(医学版)》 2008年第4期271-273,共3页 Journal of Nantong University(Medical sciences)
关键词 亚急性甲状腺炎 GRAVES病 甲状腺毒症 FT_4/FT_3 血肌酐 Subacute thyroiditis Graves disease Thyrotoxicosis FT_4/FT_3 ratio Serum creatinine
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