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Feasibility study of marrow stromal cells transplantation into guinea pig cochlea 被引量:1

Feasibility study of marrow stromal cells transplantation into guinea pig cochlea
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摘要 Objective This pilot-study was designed to evaluate the feasibility of cell transplantation into guinea pig cochlea. Methods Marrow stromal cells were labeled with DAPI, and then implanted into the cochlea of guinea pig.The existence and differentiation trend were observed roughly two weeks later by histologic analysis. Results Transplant-derived marrow stem cells survived in cochlea two weeks later with a trend of attaching to cochlear architecture but not differentiate into neuron. Conclusions Transplant-derived marrow stem cells can survive in cochlea,and cell transplantation may be a useful strategy in inner ear diseases.
出处 《Journal of Central South University of Technology》 2005年第z1期313-316,共4页 中南工业大学学报(英文版)
基金 Project(30000094) supported by the National Nature Science Foundation of China project supported by the PostdoctoralFoundation of Central South University
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  • 1Weiss MA, Frisancho JC, Roessler BJ, et al. Viral-mediated gene transfer in t he cochlea[J]. Int J Dev Neurosci,1997,15:577.
  • 2Staecker H,Li D, O'Malley BW Jr,et al. Gene expression in the mammalian coch lea: a study of multiple vector systems[J]. Acta Otolaryngol,2001,121: 1 57.
  • 3Willott JE, Turner JG, Carlson S,et al. The BALB/C mouse as an animal model for progressive sensorineural hearing loss[J]. Hear Res,1998,115:162.
  • 4Jimenez AM, Stagner BB, Martin GK,et al. Age-related loss of distortion prod uct otoacoustic emission in four mouse strains[J]. Hear Res,1999,138:91.
  • 5Kuang R, Hever G, Zeejic G,et al. Glial cell line-derived neurotrophic facto r potential for otoprotection[J]. Ann N Y Acad Sci,1999,884:270.
  • 6Yagi M, Magal E, Sheng Z,et al. Hair cell protection from aminoglycoside oto toxicity by adenovirus-mediated overexpression of glial cell line-derived neurot rophic factor[J].Hum Gene Ther,1999,10:813.
  • 7Stover T, Yagi M, Raphael Y,et al. Cochlear gene transfer: round window vers us cochleostomy inoculation[J]. Hear Res,1999,136:124.
  • 8Yamasoba T, Yagi M, Roessler BJ,et al. Inner ear transgene expression after adenoviral vector inoculation in the endolymphatic sac[J]. Hum Gene Ther,1999 ,10:769.
  • 9Stover T, Yagi M, Raphael Y,et al. Transduction of the contralateral ear af ter adenovirus-mediated cochlear gene transfer[J]. Gene Ther,2000,7: 377.
  • 10王枫,高下,黄维国,高磊,李秦,王锦铃.国产C57和BALB/c小鼠年龄相关性听力损失的畸变产物耳声发射检测[J].听力学及言语疾病杂志,2001,9(4):227-229. 被引量:6

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