摘要
目的探讨氟伐他汀与血脂康对高脂血症合并脑梗死患者血脂水平的影响。方法120例急性脑梗死患者,血脂符合高脂血症的标准,随机分为3组,分别给予氟伐他汀40mgqn、血脂康0.6mgbid及安慰剂,治疗60d后检测血脂、血清一氧化氮(NO)及氧化低密度脂蛋白(ox-LDL)浓度的变化。结果氟伐他汀组与血脂康组胆固醇、甘油三脂、LDL、ox-LDL较治疗前下降,NO及HDL明显上升(均P<0.01),与对照组相比有统计学意义,两组间差异无显著性(P>0.05)。结论氟伐他汀与血脂康在高脂血症合并脑梗死患者中不仅具有明显调节血脂的作用,并且有抗脂质氧化,保护血管内皮的功能,还可以治疗急性脑梗死。
Objective To investigate the effect of Fluvastatin and Xuezhikang on serum lipid in patients with Cerebral Infarction and Hyper Lipidemia.Methods 120 patients with acute cerebral infaction and hyper lipidemia were randomly divided into three groups: treated with Fluvastatin 40mgqn(40 cases),Xuezhikang 0.6bid(40 cases) and placebo(40 cases)for 60 days,the level of blood lipids. No and ox-LDL measured before and after the treatment.Results The tolal cholesterol(TC),triglyceride(TG),low density liporotein (LDL...
出处
《中外医疗》
2008年第25期11-12,共2页
China & Foreign Medical Treatment
关键词
氟伐他汀
血脂康
脑梗死
血脂
Fluvastatin
Xuezhikang
Ccrebral infaction
Lerum lipids
