摘要
目的 总结脐血梁色体异常的类型。方法 对86例有产前诊断指征的孕妇,在妊娠19-35w时,行脐带穿刺术抽取脐血进行染色体核型分析。结果 染色体异常核型6例,检出率为6.98％;其中21三体3例,18三体1例,染色体变异2例。结论 染色体三体,尤其是21三体为最主要的胎儿染色体异常核型,而通过产前筛查、产前诊断的方法可以有效降低先天性缺陷患儿出生。
Objective: To analyze the abnonnal chromosomal karyotypes in fetal blood samples by cotdocentesis. Methods: 86 pregnant with the indications of prenatal diagnosis during 19-35gestational weeks. The samples of fetal blood were taken and chromosomal karyotyoes were analyzed. Results: 6 abnonnal chromosomal karyotypes were found and the abnormal rate was 6.98% .There were 3 cases of trisomy. There was 1 case of Trisomy18 .There were 2 cases of chromosomal aberration. Conclusion: Trisomy .eslecially trisomy 21 ...
出处
《中国优生与遗传杂志》
2004年第S1期43-46,共2页
Chinese Journal of Birth Health & Heredity
关键词
产前诊断
脐血
染色体核型
Antenatal diagnosis
Cord blood
Chromosomal karyotype
