摘要
The reaction of diethyl malonate with various substituted 1,2-allenic ketone can be catalyzed by 10% of K2CO3leading to polyfunctionalized β, γ-unsaturated enones 3 or 4. With 3-unsaturated 1-substituted-1, 2-allenic ketones, the highly selective formation of β, γ-unsaturated enones 4 was observed; with 1,2-allenic ketones with one or two γ-substituents, only β, γ-unsaturated enones 3 with an unmigrated carbon-carbon double bond were produced; with γ-monosubstituted-1,2-allenic ketones the corresponding (E)-3 were formed highly selectively; with propadienyl ketones, a mixture of β, γ-unsaturated enones 3 and 4 were formed.……
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2003年第z1期214-214,共1页
Chinese Journal of Organic Chemistry
基金
Project supported by the National Natural Science Foundation of China, the Major State Basic Research Development Program (No. G2000077500), and Hong Kong Qiu Shi Foundation of Science and Technology (1999 ～ 2003).
