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膝骨性关节炎的中医辨证分型与膝关节镜下病理改变对比性研究 被引量:20

The comparative study on the classification of osteo-gonathritis with differentiation of symptoms and signs in TCM and their pathological changes under knee arthroscopy
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摘要 目的 对比性地研究膝骨性关节炎中西医诊断相关性。方法 对 6 0例膝骨性关节炎患者进行中医辨证 ,分三型 :Ⅰ型 ,肝肾不足 ,筋脉瘀滞型 (2 1例 ) ;Ⅱ型 ,脾肾两虚 ,湿注骨节型 (18例 ) ;Ⅲ型 ,肝肾亏虚 ,痰瘀交阻型 (2 1例 )。然后进行关节镜下病理改变观察 ,同时进行组织学病理改变观察。结果  6 0例病人均有不同程度的关节软骨面退行磨损或剥脱。 18例Ⅱ型的滑膜增生或炎性变与Ⅰ、Ⅲ型比较差异有显著性意义 ,P <0 0 1。 2 1例Ⅲ型的骨赘增生与Ⅰ、Ⅱ型比较差异有显著性意义 ,P <0 0 1。结论 脾肾两虚、湿注骨节型与镜下滑膜增生及炎性变有较密切临床诊断意义 ;肝肾亏虚、痰瘀交阻型与镜下骨赘增生有较密切临床诊断价值。 Objective To make a comparative study on the diagnosis of osteo-gonarthritis with the interrelationship of TCM and Western Medician Methods 60 cases aged from 35 to 80 years old are studied.According to the theory of diagnosis and treatment based on overall analysis of symptoms and signs of TCM,these patients are divided into three types:Type Ⅰ,insufficiency of the liver and kidney,type of stagnation of tendons and muscles(21 cases);Type Ⅱ,insufficiency of both the spleen and the kidney,type of dampness infusion into bone and joints(18 cases);Type Ⅲ,deficiency of the liver and kidney,type of inter-obstruction of phlegm and stasis(21 cases).The clinical observations of pathological changes under knee arthroscopy and comparative studies on histo-pathological changes were been undertaken,in meanwhile.Results The degeneration of the joint cartilage of the three types of patients were in different degree.The grade of the proliferation or inflammation of synovia of type Ⅱ is the highest among the three types(P<0.01).The grade of hyperosteogenesis of type Ⅲ is the highest among these three types(P<0.01).Conclusion There were close relationship of clinical diagnoses between insufficiency of both the spleen,type of dampness infusion into bone and joints,with microscopic synovial prolification or inflammative changes;and between the deficiency of both liver and kidney,type of inter-obstruction of phlegm and stasis with osteoprolification,under knee arthroscopy.
机构地区 贵阳中医学院
出处 《中国骨伤》 CAS 2003年第7期393-394,共2页 China Journal of Orthopaedics and Traumatology
基金 2 0 0 1年贵州省卫生厅资助课题 ([2 0 0 1 ] 2 1 6号 )
关键词 骨关节炎 膝关节 病理过程 对比研究 Osteoarthritis Knee joint Pathologic processes Comparative study
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