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白介素2联合CP方案治疗多发性骨髓瘤21例疗效分析

Therapeutic Analyses of IL-2 Combined with CP Scheme in Multiple Myeloma:21 Cases Report
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摘要 目的:观察白介素2联合环磷酰胺、泼尼松(CP方案)治疗多发性骨髓瘤(MM)的临床疗效。方法:对照组32例患者予MP方案(马法兰8 mg/m2,d1-7,泼尼松60 mg/m2,d1-7,3 w一个疗程,治疗6个疗程;治疗组(白介素2联合CP方案)21例患者,白介素250万u/d,d1-7,环磷酰胺(CTX),200 mg/d,d1-7,泼尼松60 mg/m2,d1-7,7~14 d一个疗程,治疗6个疗程。结果:对照组32例患者的总有效率21.9%(7例),CR率6.3%(2例);治疗组21例患者的总有效率52.3%(11例),CR率19%(4例)。两组对照有明显统计学意义(P<0.01)。结论:白介素2联合CP方案治疗MM有效。 Objective:To observe IL-2 combining cyclophosphamide and prednisone(CP Scheme)to cure MM.Methods:32 cases of comparison group are given MP scheme(Melphalan 8 mg/m2,d1-7.Prednisone 60 mg/m2,d1-7,3W as one course,6 courses);21 cases of treatment group are given CP scheme combined with IL-2,IL-2 50 ten thousand u/d d1-7,Cyclophosphamide(CTX)200 mg/d,d1-7,prednisone 60 mg/m2,d1-7,7~14 d as one course,6 courses.Results:The effective rate of 32 cases in comparison group is 21.9%(7 cases),the CR rate is 6.3%(2 cas...
出处 《华西医学》 CAS 2008年第5期1039-,共1页 West China Medical Journal
关键词 白介素2 多发性骨髓瘤 疗效 IL-2 multiple myeloma curative effect
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