摘要
目的:评价天麻素联合氟桂利嗪预防偏头痛发作的效果及其安全性。方法:半随机对照临床研究。凡符合入选标准的患者按就诊顺序随机分为两组:试验组予以氟桂利嗪5 mg/次,1次/日,睡前服用;天麻素胶囊50 mg/次,3次/日;连续服用30天;对照组:氟桂利嗪5 mg/次,1次/日,睡前服用,连续服用30天。观察治疗前后头痛发作频率、头痛程度、头痛持续时间变化,评价预防效果。结果:两组治疗后头痛发作频率、头痛程度、头痛持续时间均较治疗前改善(P<0.05);试验组受试者治疗后头痛发作频率、头痛持续时间的改善情况优于对照组,两者比较有统计学意义(P<0.05),两组均未发生严重不良反应。结论:天麻素联合氟桂利嗪预防偏头痛发作的效果及安全性良好。
Objective:To evaluate the efficacy and safety of Gastrodine combined with Flunarizine in the prophylaxis of migraine.Methods:Patients consistent with the inclusion criteria were included in the trial.122 patients were enrolled.Patients were randomized by their visiting order into two groups:the experimental group was treated with flunarizine(5 mg once daily)and Gastrodine(50 mg three times daily),and the control group was only treated with 5mg of flunarizine per day.The patients were treated for 1 month con...
出处
《华西医学》
CAS
2008年第5期1031-1032,共2页
West China Medical Journal
