摘要
目的分析小口径聚氨酯人造血管的微观形态,探讨聚氨酯人造血管管壁厚度对其渗透性能和拉伸强度的影响。方法通过在直径为4mm玻璃棒模具上复合均匀厚度的聚氨酯膜,并加入一定量的致孔剂,研制出具有微观多孔结构的小口径聚氨酯人造血管。采用扫描电镜表征其微观多孔结构,根据ISO7198国际标准设计了一套人造血管渗透性能的测试装置来测试其水渗透性能,并通过INSTRON万能强力仪(型号:5566)测试其拉伸强度。结果小口径的聚氨酯人造血管的内、外表面以及截面均呈微孔结构,微孔的大小在100μm以下,大小和分布比较均匀,并且随着人造血管壁厚度的增加,其渗透性能逐渐减小,拉伸强度先增大后减小,实验测试结果均与国外研究在同一范围。结论用聚氨酯材料研制的小口径人造血管在部分生物力学性能方面能满足人体血管置换要求。
Objective To analyse the microcosmic structure of small-diameter PU vascular graft and explore the influence by the wall thickness of vascular graft on its porous properties and tensile stress.M ethods The small- diameter vascular graft with microporous structure was prepared by casting polyurethane (PU) film onto the glass rod model. The microporous structure was charactered by SEM. According to ISO [7198], the testing equipment for such PU vascular graft was designed to test its porous property. The tensi...
出处
《医用生物力学》
CAS
CSCD
2008年第4期270-274,共5页
Journal of Medical Biomechanics
关键词
聚氨酯
人造血管
渗透性能
拉伸强度
Polyurethane
Vascular graft
Porous property
Tensile stress
