摘要
研究肝癌患者手术前后LAK、NK细胞活性和T细胞亚群免疫功能的动态变化 ,检测了 31例肝癌患者手术前后和 30例正常成人志愿者的淋巴因子活化性杀伤细胞 (LAK)、自然杀伤细胞 (NK)活性以及T淋巴细胞亚群较肝癌患者的LAK、NK活性以及CD3、CD4和CD4 /CD8比值均明显降低 (P <0 0 1) ,CD8有增高趋势 (P >0 0 5 ) ;术后 16d ,上述细胞免疫活性与术前相比显著增高 (P <0 0 5 )。结果细胞免疫功能在肝癌患者中严重受损并且与肿瘤的消长有密切关系 ,LAK、NK、TC细胞亚群活性为判断肝癌手术疗效和预后的重要指标 。
To investigate the changes of immunological function of LAK,NK cell activity and T lymphoctyes subsets before and after operation in patients with hepatic cancer.The activity of Lymphokine-activated Killer Cell (LAK|,Natural Killer Cell(NK) and T lymphocytes subsets were detected in 31 patients with hepatic cancer of preoperation and postoperation,so did the 30 normal volunteers(as control group).The results showed that the activities of LAK,NK cell and T lymphocytes subsets of CD3,CD4 and the ratio of CD4/...
出处
《中国医师杂志》
CAS
2002年第S1期6-8,共6页
Journal of Chinese Physician
