摘要
目的 研究和开发国产支架型人工血管经腔内治疗动脉疾病。方法 1993年 6月至 1999年 8月 ,用北京地区杂种狗 2 4条 ,分别制作了腹主动脉瘤 ( 8条 )、降胸主动脉瘤 ( 6条 )、升主动脉瘤 ( 4条 )、主动脉弓瘤 ( 4条 )和动静脉瘘 ( 2条 )模型 ,用自制的支架型人工血管置入。置于腹主动脉的支架是编织式镍钛合金记忆金属 ,长 3cm ,直径 8cm ;胸主动脉支架是联体不锈钢“Z”型支架 ,长 3cm ,直径 2cm。覆膜均为国产超薄涤纶人工血管。临床应用 2 0例 ,男 17例 ,女 3例。主动脉夹层 11例 ,肾下腹主动脉瘤 7例和创伤性动静脉瘘 2例。结果 17条狗术后存活 ,分别于 2、4、8周获取标本 ,支架型人工血管通畅良好 ,无血栓形成。临床病例中 ,有 1例腹主动脉瘤并发肾功能不全 ,于术后 2 0天血液透析中死于心肌梗塞 ,其余病人均被成功治疗。随访 2个月至 5年 ,除 1例夹层动脉瘤术后 3个月支架移位外 ,所有病人恢复良好。结论 自制的支架型人工血管费用低 ,操作简便 ,应用前景可观。
Objective The Chinese stenting graft in vascular surgery was developed and studied.Methods The animal models of 24 mongrels in Beijing area were established including abdominal aortic aneurysm(AAA,8), descending thoracic aortic aneurysm(6),ascending aortic aneurysm(4),aneurysm of aortic arch(4) and tramatic arteriovenous fistulae(2). The stenting graft was made of knitted NiTi alloy or stainless steel and ultrathin Dacron in this hospital. A total of 20 patients with aortic dissection(11), abdominal aneurysm(7) and traumatic AVF(2) were applied with the stenting graft.Results The 17 dogs were survival after operation and sacrified at 2,4, and 8 weeks. The stenting grafts were sampled and examinated that there were patent and no thrombosis. In clinical cases, the death occurred in one patient with AAA due to renal failure and mycardic infarction. The other patients were cured successfully.Conclusion The stenting graft is very cheap, convenient in operating with low cost and its application prospects are very bright.
出处
《生物医学工程与临床》
CAS
2001年第4期198-200,共3页
Biomedical Engineering and Clinical Medicine
关键词
支架
人工血管
腔内治疗
stenting graft
endovascular surgery
artifical vascular
