摘要
天然免疫是机体抵御病原微生物感染的第一道防线。首先机体要识别病原体然后才能做出防御性反应。目前发现 :Toll样受体家族成员在识别病原体并介导天然免疫反应中具有重要作用。TLR结构及功能的研究 。
The innate immune response is the first line of defense against infectious disease by recognizing the invading pathogens and mounting a rapid defensive response. Recent studies have revealed that Toll like receptors (TLRs) are key molecules for recognizing bacterial components to evoke innate immune response. Studies on TLRs and their signaling pathway will disclose the mechanism of innate immune reco gnition and host defense.
出处
《免疫学杂志》
CAS
CSCD
北大核心
2001年第z1期17-20,共4页
Immunological Journal
关键词
TLR
天然免疫
Toll like receptor (TLR)
innate immunity
