摘要
目的探讨适合割宫产术后镇痛的理想方案。方法360例孕妇需剖宫产者分为静脉镇痛组和硬膜外镇痛组(吗啡组、芬太尼组),随机分为三组,每组120例,静脉镇痛组(Ⅰ组):芬太尼0.8mg+氟哌利多2.5mg+NS至100mL,2mL/h;硬膜外镇痛组(芬太尼组) (Ⅱ组):芬太尼0.8mg+0.75%左旋布比卡因10mL+NS至100mL,2mL/h;硬膜外镇痛组(吗啡组)(Ⅲ组):吗啡6mg+0.75%左旋布比卡因10mL+盐酸异丙嗪12.5mg+NS至60mL,1mL/h,手术结束前10min硬膜外腔给饱和量(吗啡1.5mg+盐酸异丙嗪5mg+NS至10mL,根据产妇情况一次注入7~10mL)。结果各组镇痛效果差异明显,硬膜外镇痛吗啡组>硬膜外镇痛芬太尼组>静脉镇痛组,不良反应发生率Ⅰ组稍高于Ⅱ组,Ⅱ组稍高于Ⅲ组(P<0.05),皮肤搔痒发生率Ⅲ组稍大于Ⅰ、Ⅱ组(P>0.05),锥体外系发生率Ⅰ组大于Ⅱ、Ⅲ组(P<0.05).结论硬膜外吗啡镇痛组效果优良,不良反应发生率低,易于产妇接受,适宜制宫产术后镇痛.
Objective To study an ideal program which is suitable for analgesia after caesarean operation.Method To divide 360 pregnant women who need caesarean operation into intravenous analgesia group and epidural analgesia group(Morphine Group and Fentanyl citrate ingection Group) in random with 120 women each group,intravenous analgesia group(GroupⅠ):give an injection of 0.8mg fentanyl+2. 5mg droperidol ingection+NS up to 100mL with a speed of and per hour.Epidural Analgesia Group (Fentanyl citrate ingection Group) (GroupⅡ):give an injection of 0.8mg fentanyi citrate ingection +10mL levobupivacaine ingection whose density is 0.75%+NS up to 100mL with a speed of 2mL per hour.Epidural Analgesia Group (Morphine Group) (GroupⅢ):give an injection of 6mg morphine+10mL lerobuicacaine ingection whose density is 0.75%+12.5mg promethazine hydrochloride ingection+ +NS up to 60ml with a speed of 1mL per hour.The operation lasted about 10 minutes before the epidural space was given a eatarable amount(1.5mg morphine+5mg promethazine hydrochloride ingection+NS up to 10mL.Give an injection of 7~10mL each time according to the pregnant women' s situation.) Results The differences in the analgesia effects of each group is obvious.Epidural Morphine Group>Epidural Fentanyl ingection Group>Intravenous Group The rate of side effects in GroupⅠis slightiy larger than GroupⅡwhile the rote of side effects in GroupⅡis slightly larger than GroupⅢ(P<0.05).The rate of outside of the vertebal in GroupⅠis larger than GroupⅡand GroupⅢ(P>0.05).Conclusion Epidural Morphine Analgesia Group is suitable for analgesia after Caesarean Operation and easily accepted by the pregnant women because of its excellent effects and low side effects.
出处
《中国医药指南》
2008年第17期39-40,共2页
Guide of China Medicine
关键词
剖宫产
术后镇痛
比较
Caesarean operation
Analgesia after operation
Comparison