摘要
目的磁共振成像(MRI)是目前诊断新生儿脑梗死的金标准,然而常规MRI对于2d内的新生儿脑梗死的早期显像并不敏感。为了早期诊断新生儿脑梗死,该研究探讨了新生儿脑梗死患儿的早期临床表现及头部MRI成像学特征,包括常规MRI及弥散加权成像(DWI),并为早期诊断提供依据。方法回顾分析该院新生儿病房收治的16例新生儿脑梗死患儿临床资料、头部MRI检查(所有病例均于生后5d内行常规序列扫描后接受弥散加权序列扫描),其中5例于新生儿期(生后11～18d)进行了第2次头部MRI检查。结果①高危因素:产前8例(50%),产时9例(56%),产后0例(0%);临床表现:11例以惊厥发作为首发症状,患儿每次抽搐持续时间较短(平均为2～3min),9例于24h内停止抽搐;②MRI扫描结果:初期(5d内)病灶部位T1稍低信号,T2加权稍高信号,相同部位弥散加权影像均表现为高亮信号,且病灶边界清晰;再次扫描时(生后11～18d)病灶部位T1低信号、T2高信号较前明显,相同部位弥散加权均表现为低信号。结论惊厥多为新生儿脑梗死的首发表现,发作次数少且程度轻;梗死早期DWI表现为高亮信号,继之常规MRI出现T1低信号、T2高信号,并随时间逐渐明显,尤以T2表现更为敏感。
Objective The present study aimed to characterize the clinical presentations and magnetic resonance imaging including conventional MRI and diffusion-weighted imaging(DWI)in newborns with cerebral infarction.Methods Clinical records of 16 newborn infants with cerebral infarction were reviewed.All cases underwent DWI examination in addition to conventional MRI examination [T1-weighted(T1W)and T2-weighted(T2W)] within 5 days after birth.Five patients received the second MRI examination at the age of 11 to 18 d...
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2009年第2期96-99,共4页
Chinese Journal of Contemporary Pediatrics
关键词
脑梗死
磁共振成像
弥散加权成像
婴儿
新生
Cerebral infarction
Magnetic resonance imaging
Diffusion-weighted imaging
Newborn
