摘要
目的了解儿童患者临床分离的铜绿假单胞菌的耐药情况。方法用纸片扩散法对12种抗菌药物进行药物敏感试验。用WHONET5.3软件分析耐药情况。结果本研究获得的590株铜绿假单胞菌主要分离自下呼吸道标本365株(69.1%)。铜绿假单胞菌对环丙沙星的耐药率最低为0.7%;除阿米卡星(2.1%)、庆大霉素(4.9%)、头孢吡肟(5.2%)外,铜绿假单胞菌对其他所测抗菌药物的耐药率都在20%以上,且增高明显(P<0.01)。ICU分离到铜绿假单胞菌的耐药情况要比其他病区严重。多重耐药铜绿假单胞菌的检出率由13.3%增加到26.9%。结论儿童临床分离的铜绿假单胞菌对抗菌药物的耐药有增高趋势,多重耐药铜绿假单胞菌增加。应合理使用抗生素,控制和降低细菌耐药性的产生。
Objective To investigate the antibiotic resistance of P.aeruginosa strains isolated from children infecttions.MethodsKirby-Bauer method was used to determine the susceptibility of the P.aeruginosa isolates to 12 commonly used antibiotics.WHONET 5.3 software was used to analyze the data.ResultsPrevalence of P.aeruginosa was 8.8%(590/6735)in clinical specimens.P.aeruginosa was most sensitive to ciprofloxacin(0.7% resistant).Other antibiotics showed significantly higher resistance rate than amikacin,gentamicin...
出处
《中国感染与化疗杂志》
CAS
2009年第1期63-66,共4页
Chinese Journal of Infection and Chemotherapy
关键词
儿童
铜绿假单胞菌
多重耐药
children
Pseudomonas aeruginosa
multiple resistance
