摘要
目的:探讨舒芬太尼复合丙泊酚用于无痛结肠镜检查的可行性及优越性。方法:100例拟行无痛结肠镜检查的患者,随机分为芬太尼组(PF组)和舒芬太尼组(PS组),每组50例。两组分别缓慢静脉注射芬太尼1μg/kg、舒芬太尼0.1μg/kg后静脉匀速推注丙泊酚1mg/kg～1.5mg/kg,睫毛反射消失后开始检查操作。术中视情况追加丙泊酚0.5mg/kg～1.0mg/kg。连续监测用药前及用药后1min、3min、5min、7min的心率(HR)、收缩压(SBP)、舒张压(DBP)、氧饱和度(SPO2),并记录停药睁眼时间,定向力恢复时间,丙泊酚总用量、副作用及结肠镜检查结果。结果:两组丙泊酚总用量、定向力恢复时间、麻醉效果相似(P>0.05),但停药睁眼时间PS组比PF组快(P<0.01)。用药后收缩压(SBP)、舒张压(DBP)、心率(HR)降低幅度无统计学意义(P<0.05)。结论:舒芬太尼复合丙泊酚用于无痛结肠镜检查,麻醉效果优且不良反应少,舒适性好,便于结肠镜检查的诊断操作。
Objective:To study the feasibility and superiority of sufentanil combined with propofol in painless colonoscopy.Methods: 100 patients undergoing colonoscopy were randomly allocated into two groups. In group PF(n=50), 1μg/kg fentanil was slowly injected intravenously followed by propofol 1-1.5mg/kg. In group PS(n=50), 0.1μg/kg sufentanil was slowly injected intravenously followed by propofol 1-1.5mg/kg. Propofol of 0.5-1.0mg/kg was added during the operation when necessary. HR, SBP, DBP, SPO2 were continuous...
出处
《肿瘤预防与治疗》
2009年第1期54-56,共3页
Journal of Cancer Control And Treatment
