摘要
目的 探讨米非司酮配伍米索前列醇用于 9～ 2 4周妊娠引产的效果。 方法 16 8例 9～ 2 4周妊娠妇女 ,口服米非司酮 75 m g,每 12 h 1次 ,共 2次。末次服药后 1h,阴道后穹窿置米索前列醇 2 0 0μg,间隔 4h重复给药。按孕周分四组观察。 结果 引产成功率 (% )分别为 95 .12 ,10 0 ,96 .6 7,97.96 ,四组比较差异无显著性 (P>0 .0 5 )。产后出血量 (ml)分别为 6 8.2 1± 14.2 1,89.2 5± 2 6 .47,117.18± 18.73,12 6 .2 4± 2 5 .16 ,与孕周呈正相关 (P<0 .0 1)。引产时间(h)分别为 8.0 5± 2 .0 2 ,11.2 7± 4.2 9,15 .35± 1.17,2 1.2 3± 3.32 ,与孕周呈正相关 (P<0 .0 1)。米索前列醇用量 (μg)分别为 5 0 0 .14± 82 .13,490 .0 6± 10 4.2 5 ,5 74.82± 93.0 6 ,482 .5 1± 12 1.34 ,各组米索前列醇用量无显著差异且与孕周无相关 (P>0 .0 5 )。 结论 米非司酮配伍米索前列醇用于 9～ 2 4周妊娠引产有效而且安全。引产时间和出血量与孕周有关。
Objective\ To investigate the efficiency of mifepriston and misoprostol for labor induction in the 9～24 week pregnancy.\ Methods\ 168 women with 9～24 week pregnancy took 75 mg mifepriston every 12 hours for two times.\ One hour after last mifepriston,200 μg misoprostol was placed in posterior vaginal fornix every 4 hrs.\ According to pregnancy term,all the cases were divided into 4 groups.\ Results\ The success rats of induction labor were 95 12%,100%,96 67% and 97 96%.\ There were no statistics signific...
出处
《福建医科大学学报》
2000年第S1期35-37,共3页
Journal of Fujian Medical University
关键词
米非司酮
米索前列醇
引产
mifepriston
misoprostol
induction
pregnancy
