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比索洛尔治疗慢性心力衰竭的临床观察 被引量:1

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摘要 目的 评价比索洛尔治疗慢性心力衰竭(CHF)的疗效及对心室重塑、血流动力学等的影响.方法 70例(CHF)患者随机分为对照组(n=35)、治疗组(n=35).所有患者均根据病情给予洋地黄、利尿剂、血管紧张素转换酶抑制剂(ACEI)等基本治疗,治疗组同时给予比索洛尔治疗(4个月),比较两组治疗前后临床症状和血流动力学参数变化.结果 两组患者治疗前年龄、性别、病因无统计学差异,比索洛尔治疗4个月后NYHA心功能显著改善,左室舒张末期内径明显缩小,左室射血分数(LVEF)对照组由(38.1±7.5)%增至(42.1±7.5)%,而治疗组由(39.8±9.7)%增至(47.5±7.1)%,有显著性差异,P<0.01.结论 选择β1受体阻滞剂比索洛尔治疗能减轻CHF患者临床症状,改善心功能,改善心室重塑.
作者 何晓薇
出处 《中国中医药现代远程教育》 2009年第6期30-31,共2页 Chinese Medicine Modern Distance Education of China
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  • 1Benjamin EJ, Wolf PA, D'Agostino RB, et al. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study[J]. Circulation,1998,98: 946.
  • 2Dries DL, Exner DV, Gersh BJ, et al. Atrial fibrillation is associated with an increased risk for mortality and heart failure progression in patients with asymptomic and symptomic left ventricular systolic dysfunction: a retrospective analysis of the SOLVD trials[J]. J Am Coll Cardiol,1998,32: 695.
  • 3MERIT-HF Study Group.Effect of metoprolol CR/XL in chronic heart failure:metoprolol CR/XL randomized intervention trial in congestive heart failure (MERIT-HF)[J].Lancet,1999,353: 2001.
  • 4Helmcke F,Nanda NC,Hsiung MC,et al.Color Doppler assessment of mitral regurgitation with orthogonal planes[J].Circulation,1987,13: 585.
  • 5Jose A, Joglar MD, Andre PA, et al.Effects of carvedilol on survival and hemodynamics in patients with atrial fibrillation and left ventricular dysfunction:retrospective analysis of the US carvedilol heart failure trials program[J].Am Heart J,2001,142: 498.
  • 6CIBIS-Ⅱ Investigators and Committees.Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial[J].Lancet,1999,353: 9.
  • 7Paul D, Jonathan M, Pieo B, et al. Effects of bisoprolol fumarate on left ventricular size, function, and exercise capacity in patients with heart failure:analysis with magnetic resonance myocardiol tagging[J].Am Heart J,2002,143: 676.
  • 8Soccorso C, Oreste F, Marco M, et al.β-blocker therapy in chronic heart failure :diastolic function and mitral regurgitation improvement by carvedilol[J].Am Heart J,2000,139:596.
  • 9Todd MK, Keith DA, Robert JC, et al. Prognostic significance of mitral regurgitation and tricuspid regurgitation in patients with left ventricular systolic dysfunction[J]. Am Heart J,2002,144: 524.
  • 10Yoshikawa T,Port JD,Asano K,et al.Cardiac adrenergic receptor effects of carvedilol[J].Eur Heart J,1996,(Suppl B): 8.

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