摘要
目的:研究急性中毒患者血清肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)的水平及其临床意义。方法:采用ELISA法检测36例急性中毒患者血清TNF-α及IL-6含量。结果:36例急性中毒患者血清TNF-α及IL-6含量均显著高于正常对照组(P<0.05),并随病情加重而增高。结论:TNF-α及IL-6参与了急性中毒的发病过程,测定其含量有助于急性中毒患者的病情评估及预后判断。
Objective: To investigate the significance of plasma tumor necrosis factor-α(TNF-α) and interleukin-6(IL-6) levels in acute poisoning. Methods: ELISA methods were used to determine the TNF-α、IL-6 levels in acutepoisoning. Results: Plasma TNF-α、IL-6 levels in the patients with acute poisoning were significantly higher than the levels inthe healthy subjects (P<0.01). Conclusions: TNF-α, IL-6 play important roles in acute poisoning. The assay of themmay be helpful for evaluation of acute poisoning and prognosis.
出处
《岭南急诊医学杂志》
2001年第4期256-257,共2页
Lingnan Journal of Emergency Medicine
关键词
急性中毒
TNF-Α
IL-6
acute poisoning
tumor necrosis factor-α(TNF-α)
interleukin-6(IL-6)
