摘要
目的分析新生儿呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)的高危因素、病原菌及药敏情况,探讨临床降低VAP发病率的策略。方法回顾分析2000年1月至2004年12月机械通气超过48h的116例新生儿,其中VAP49例,比较上机时间、插管次数、胎龄、机械通气模式以及分析病原学监测结果。结果VAP的发病率为42.2%;VAP组上机时间和插管次数明显多于非VAP组;不同胎龄儿VAP的发生率统计学无显著性差异;SIMV/SIPPV模式VAP的发生率低于IMV/IPPV模式;致病菌以克雷伯杆菌、大肠杆菌、铜绿假单孢杆菌为主。结论VAP是多因素综合作用的结果,必须重视并预防VAP,采取综合措施减少VAP的发生。
Objective The high-risk factors and the pathogens of neonatal ventilator-associated pneumonia were analyzed to inquire into the tactics of how to reduce the incidence of the disease.Methods Retrospective study was conducted in 116 infants given mechanical ventilation for longer than 48 hours from Jan.2000 to Dec.2004.Among the 116 infants,49 with VAP were compared to 67 without VAP in terms of the duration using mechanical ventilation,the times of inserting tube,the gestational age,the mode of mechanical ventilation and the bacteria culture results.Results The overall incidence of VAP was 42.2%; Infants with VAP had a longer ventilation time and more times of inserting tube; The difference of gestational age between the 49 with VAP and the 67 without VAP was not statistically significant; the rate of VAP in the group with SIMV/SIPPV was lower than that with IMV/IPPV; Klebsiella pneumoniae,E.coli and Pseudomonas aeruginosa were the main pathogenic bacteria.Conclusion VAP is caused by more than one factors.Synthetical tactics can reduce the incidence of the VAP.
出处
《中国实用医药》
2007年第13期32-33,共2页
China Practical Medicine
关键词
新生儿
呼吸机相关性肺炎
临床分析
Nonatal
Ventilator-associated pneumonia
Clinic analysis
