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112例辛伐他汀治疗高脂血症疗效观察

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摘要 目的观察辛伐他汀(博占同)治疗高脂血症的临床疗效。方法对112例高脂血症患者给予口服辛伐他汀20mg/d,治疗8周,治疗前后分别测定胆固醇(TC),三酰甘油(TG),低密度脂蛋白胆固醇(LDL-C)等。结果治疗前后血脂水平比较差异有统计学意义(P<0.01),治疗后血脂降低效果明显。服药期间部分患者出现消化道反应及一过性ALT,AST增高等不良反应。结论辛伐他汀调脂疗效好,不良反应少。
作者 张丽红 黄进 王冬元
机构地区 辽宁沈阳二四二医院心内科
出处 《中国实用医药》 2007年第21期38-39,共2页 China Practical Medicine
关键词 辛伐他汀 高脂血症 血脂 不良反应
分类号 R589.2 [医药卫生—内分泌]
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  • 1[1]Scandinavian Simvastatin Survival Study Group. Randomise d trial of choles terol lowering in 4 444 patients with coronary heart disease: the Scandinavian Survival Study(4S)[J]. Lancet,1994,344:1383-1389.
  • 2[2]Sacks FM,Pfeffer MA,Moye LA,et al. The effect of pravastatin on coro nary events after myocardial infarction in patients with average cholesterol evels. Cholesterol and Recurrent Events Trial Ingestigarors[ J ]. N Engl J Med, 1996,335: 1001-1009.
  • 3[3]The Long-Term Intervention with Pravastatin in Ischemie Heart Disease (LIPID)Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of ini tial cholesterol Levels[J]. N Engl J Med,1998,339:1349-1357.
  • 4[4]Shepherd J,Cobbe SM,Ford 1,et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scot[and coronary prevention Study Group[J ]. N Engl J Med, 1995,333: 130l-1307.
  • 5[5]Downs JR,Clearfield M,Weis S,et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels Re sults of AFCAPS/Tex CAPS[J]. JAMA,1998,279:1615-1622.
  • 6[6]The lipid research clinics coronary primary prevention trial results. I reduc tion in incidence of coronary heart disease[J]. JAMA. 1984,251: 351-364
  • 7[7]NCEP(National Cholesterol Education Program). Guidelines of the second adult treatment panel( ATP I )[J]. JAMA,1993,267:3015-3023.
  • 8[8]The Post Coronary Artery Bypass Graft Trial Invesugators. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low dose anticoagulation on obstructive changes in saphenous-vein coronary artery bypass grafts[J ]. N Engl J Med,1997,336:153-162.
  • 9[9]Pitt B,Waters D,Brown WV,et al. Aggressive lipid lowering therapy compared with angioplasty in stable coronary artery disease[J]. N Engl J Med,1999,341:70-76.
  • 10[10]Davignon J. Pleiotropic effects: facts and fiction XⅢ International Symposium on Atherosclerosls[R]. Sweden Stockholm: 2000-1 25～29.

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中国实用医药
2007年 第21期

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