摘要
以杜×(大×长)三元杂种猪为研究对象,将其分为2组,分别饲喂基础日粮和添加1%精氨酸日粮,测定试验猪血液白细胞分类计数、血清免疫球蛋白和细胞因子水平、淋巴细胞增殖活性以及脾脏IL-2、TNF-α和IFN-γ的mRNA表达水平,探讨日粮添加精氨酸对肥育猪免疫功能的调节作用。结果表明:日粮中添加1%精氨酸可显著增加单核细胞数和百分比、淋巴细胞百分比和增殖活性及血清IgG和IL-2水平,显著降低中性粒细胞数和百分比及血清TNF-α水平;明显增加脾脏IL-2和IFN-γ表达水平,降低TNF-α表达水平。结果提示,精氨酸可通过调节肥育猪的细胞和体液免疫水平,从而增强机体免疫功能。
This study was conducted to evaluate the effects of arginine on immune response in fattening pigs.Twenty Duroc×Landrace×Yorkshire pigs with about 50 kg of body weight were randomly assigned to 2 treatment groups(10 pigs per group) representing the addition of 0 or 1% arginine to basal diets.On 60 days after initiation of the addition,total and differential counts of leucocytes,serum levels of immunoglobulins(Ig) and cytokines,and proliferation activity of peripheral lymphocytes were determined,as well as mR...
出处
《扬州大学学报（农业与生命科学版）》
CAS
CSCD
北大核心
2009年第3期45-49,共5页
Journal of Yangzhou University：Agricultural and Life Science Edition
基金
国家重点基础研究发展计划项目(973-2004CB117502)
国家自然科学基金资助项目(30771558
30371038)
国家"十一五"科技支撑计划项目(2006BAD12B02-5-2
2006BAD12B07-6)
关键词
肥育猪
精氨酸
免疫功能
fattening pigs
arginine
immune function
