摘要
目的:探讨肝硬化(LC)患者终末期肝病模型(MELD)分值和VEGF关系及两者对预后的判断。方法:选择LC患者125例,同步测定患者血清VEGF、血清肌酐(CR)、凝血酶原时间(PT)、总胆红素(TBI)等指标,根据MELD评分公式计算出MELD分值,分析血清VEGF与MELD分值关系,以及两者对LC患者预后判断。结果:血清VEGF水平:SACLF>CLF>CLC(P<0.05,P<0.01);患者MELD分值:SACLF>CLF>CLC、CLC+PHC(P<0.05,P<0.01);LC患者血清VEGF与MELD分值呈正相关(P<0.05);死亡患者MELD分值和血清VEGF均高于好转组(P<0.05)。结论:MELD分值联合血清VEGF对LC患者预后的判断有重要意义。
Objective:To evaluate the significance of the serum vascular endothelial growth factor (VEGF) and model for end-stage liver disease (MELD) in patients with liver cirrhosis (LC). Methods:Serum VEGF,CR,PT and TBI were detected in 125 patients with LC according to the formula of MELD,and the scores of MELD were calculated. The correlations between serum of VEGF and scores of MELD were analyzed. Results:The levels of serum VEGF:SACLF>CLF >CLC (P<0.05,P< 0.01).The scores of MELD:SACLF>CLF >CLC,CLC+PHC (P<0.05,P<...
出处
《南通大学学报（医学版）》
2009年第4期242-243,246,共3页
Journal of Nantong University(Medical sciences)
基金
南通市社会发展科技计划项目(S5016)
关键词
肝硬化
终末期肝病模型
血管内皮生长因子
Liver cirrhosis
Model for end-stage liver disease
Vascular endothelial growth factor
