摘要
目的:探讨膳食及其相关因素与肺癌的关系。方法:应用病例对照研究的方法,选取开封县原发性肺癌病例130例,按性别、年龄1:1配对选取正常对照,问卷调查收集研究对象的一般情况、膳食摄入及相关情况,应用秩和检验和χ2检验进行单因素分析,应用logistic回归进行多因素分析,计算OR值及其95%可信区间(CI),筛选出肺癌的主要相关因素。结果:单因素分析发现8个暴露因素与肺癌发生有关;多因素分析发现饮食不规律(OR=5.032,95%CI1.516～16.640)、肿瘤家族史(OR=8.569,95%CI0.852～82.189)可能是肺癌的危险因素,经常摄入大米(OR=0.390,95%CI0.156～0.977)、体质指数大(OR=0.323,95%CI0.122～0.879)及家庭月人均收入高(OR=0.394,95%CI0.164～0.945)为肺癌的保护因素。结论:膳食及其相关因素中肺癌的保护因素和危险因素并存,合理膳食、规律饮食、保持理想的BMI和发展经济有助于降低肺癌的发生。
Aim:To investigate the relationship between dietary factors and lung cancer.Methods:The dietary intake and relative factors were investigated and compared between 130 cases(primary lung cancer patients)and 130 controls(matched for age and gender).The survey data were collected from well designed questionnaire.Statistical analysis of single factor and multivariate logistic regression were performed to screen the main risk factors of lung cancer.Results:During the single factor analysis,8 exposure factors wer...
出处
《郑州大学学报（医学版）》
CAS
北大核心
2009年第6期1260-1262,共3页
Journal of Zhengzhou University(Medical Sciences)
关键词
肺癌
膳食
病例对照研究
lung cancer
diet
case-control study
