摘要
目的探讨年轻妇女子宫内膜癌临床及病理特征。方法回顾分析1989年-2004年期间至绵阳中心医院就诊并手术分期的27名年轻子宫内膜癌患者(≤45岁,A组)临床病理资料,与同期手术的142名老年内膜癌患者(>45岁,B组)相对照。结果内膜癌患者中年轻患者约占11.2%,A组患者平均体重低于B组患者,肥胖发病率低于B组,多囊卵巢综合征、不孕、子宫肌瘤发病率高于B组,差异均有统计学意义;A组高血压,糖尿病,冠心病发病率低于B组,差异有统计学意义。子宫腺肌症患病率在两者之间差异无统计学意义。A组患者确诊前症状持续时间长于B组,患者病理分化及肌层浸润状况优于B组,差异均有统计学意义;临床早期患者比例、良好病理类型比例高于B组,盆腔淋巴结转移率,腹腔细胞学阳性率低于B组,但差异无统计学意义。结论年轻妇女在子宫内膜癌患者中有着相当的比例,多囊卵巢综合征,不孕为子宫内膜癌年轻患者高危因素。有月经异常,不规则阴道出血的年轻子宫肌瘤患者,应重视诊断性刮宫。由于目前尚不能肯定年轻妇女内膜癌恶性程度及远处侵袭行为优于老年患者,故淋巴结清扫处理原则应该与老年患者相同。
Objective To study The clinic and pathologic characters of young women with endometrial carcinoma.Methods Retrospectively analyze the clinic and pathologic records of 27 surgically staged young patients (age≤45 years,Group A)with endometrial cancer in MianYang central hospital, compared with 142 older patients (age>45 years,Group B)with endometrial cancer in the same term.Results 11.2% of the patients with endometrial cancer were younger than 45 years old. The average weight of group A was significantly lower than group B, so as the incidence of adiposity. The incidence of polycystic ovary syndrome, sterility and leimyoma of uterus of group A was significantly higher than group B. The incidence of hypertension, diabetes, coronary heart disease in group A was significantly lower than group B. The difference of incidence of adenomyosis between group A and group B was not significant. The mean duration of symptoms in group A was longer than group B. The pathologic differentiation and condition of muscle invasion in group A was better than group B. The proportion of clinic forepart stage and better pathologic type in group A was higher than group B. The ratio of pelvic lymph metastasis and positive of abdominal cytology in group A was lower than group B, but the difference was not significant.Conclusion There are some young women in the patients with endometrial cancer. Polycystic ovary syndrome, sterility were high risk factors of endometrial cancer in young women. Diagnostic uterine curettage should be taken in young women with abnormal menses and irregular bleeding. The difference of degree of malignancy and metastasis behavior was not significant, so the regulation of neck dissection in young patients was same to the older.
出处
《中国医药导报》
CAS
2005年第24期5-6,15,共3页
China Medical Herald
关键词
子宫内膜肿瘤
年轻妇女
肿瘤期别
肿瘤浸润
淋巴结转移
Endometrial Carcinoma Young Women Neoplasm Staging Neoplasm Invasiveness Lymphnode Metastasis
