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药物治疗脂质异常新靶点的研究进展 被引量：2

Progress on new target in medicine treatment of lipid abnormality
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摘要 血脂异常是冠心病的危险因素,本文综述了近年来关于脂质异常药物治疗新发现的作用靶点及其特异的抑制剂/激活剂的相关研究,分为影响胆固醇吸收和影响HDL-C、TG代谢两类,包括植物固醇类、二氮杂环丁酮类、ACAT抑制剂、MTP抑制剂、重组载脂蛋白AI脂质体、CETP抑制剂、LPL激活剂等,这些新靶点成为降脂药物开发的研究方向。
作者 毕楠 陈保生
机构地区 中国医学科学院/中国协和医科大学基础医学研究所
出处 《中国药物应用与监测》 CAS 2004年第4期58-61,共4页 Chinese Journal of Drug Application and Monitoring
基金 国家973资助项目(G-20000569-02)
关键词 脂质异常 动脉粥样硬化 降脂药
分类号 R589.2 [医药卫生—内分泌]
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参考文献19

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中国药物应用与监测
2004年 第4期

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