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Celiac disease in Middle Eastern and North African countries:A new burden? 被引量:2

Celiac disease in Middle Eastern and North African countries:A new burden?
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摘要 Celiac disease(CD) is now recognized as a common disorder among Middle Eastern(ME) and North African(NA) populations.The aim of this review is to assess the available data regarding CD in the ME and NA and to compare this information with that of Western countries.A literature review was performed using the electronic databases PubMed and Medline(1950-2008) as search engines,and "celiac disease" was used as a Mesh term.The search was limited to ME and NA countries.The prevalence of CD in ME and NA countries among low risk populations is similar to that of Western countries,but is higher in high risk populations such as those with type 1 diabetes.It is underestimated because of lack of clinical suspicion and lack of patient awareness.Clinical presentations in term of gastrointestinal,hematologic,skeletal,and liver manifestations are similar between both populations except for a high prevalence of short stature in some ME and NA countries.Few studies have addressed atypical or silent CD.As in the West,diagnosis is initially made by serological tests and is confirmed by small intestinal biopsies.Gluten-free diet is the main mode of treatment with a higher apparent adherence rate than in the West.Most disease complications result from malabsorption.The disease is strongly associated with HLA DQ2 and to a lesser extent with HLA DQ8 alleles.In conclusion,CD prevalence is underestimated,with little data available about its malignant complications.Disease parameters in the ME and NA are otherwise similar to those in Western countries. Celiac disease(CD) is now recognized as a common disorder among Middle Eastern(ME) and North African(NA) populations.The aim of this review is to assess the available data regarding CD in the ME and NA and to compare this information with that of Western countries.A literature review was performed using the electronic databases PubMed and Medline(1950-2008) as search engines,and 'celiac disease' was used as a Mesh term.The search was limited to ME and NA countries.The prevalence of CD in ME and NA countries...
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2010年第12期1449-1457,共9页 世界胃肠病学杂志(英文版)
关键词 Celiac disease Gluten-free diet Insulin dependent diabetes mellitus Iron defi ciency anemia Middle East Celiac disease Gluten-free diet Insulin dependent diabetes mellitus Iron defi ciency anemia Middle East
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  • 1Abdulrahman M Aljebreen,Majid A Almadi,Alwaleed Alhammad,Faleh Z Al Faleh.Seroprevalence of celiac disease among healthy adolescents in Saudi Arabia[J].World Journal of Gastroenterology,2013,19(15):2374-2378. 被引量:1
  • 2LAbenavoli,LLeggio,AFerrulli,LVonghia,GGasbarrini,GAddolorato,IProietti,RCapizzi,MRotoli,PLAmerio.Cutaneous manifestations in celiac disease[J].World Journal of Gastroenterology,2006,12(6):843-852. 被引量:5
  • 3Rahim Masjedizadeh,Eskandar Hajiani,Jalal Hashemi,Ali Akbar Shayesteh,Karim Moula,Tahereh Rajabi.Celiac disease in South-West of Iran[J].World Journal of Gastroenterology,2006,12(27):4416-4419. 被引量:1
  • 4Francesco Cataldo,Giuseppe Montalto.Celiac disease in the developing countries: A new and challenging public health problem[J].World Journal of Gastroenterology,2007,13(15):2153-2159. 被引量:16
  • 5Rohit Dixit,Benjamin Lebwohl,Jonas F. Ludvigsson,Suzanne K. Lewis,Norelle Rizkalla-Reilly,Peter H. R. Green.Celiac Disease Is Diagnosed Less Frequently in Young Adult Males[J].Digestive Diseases and Sciences.2014(7)
  • 6J. Y. Kang,A. H. Y. Kang,A. Green,K. A. Gwee,K. Y. Ho.Systematic review: worldwide variation in the frequency of coeliac disease and changes over time[J].Aliment Pharmacol Ther.2013(3)
  • 7Eugenia Lauret,Luis Rodrigo,Anne Astier.Celiac Disease and Autoimmune-Associated Conditions[J].<journal-title>BioMed Research International.2013
  • 8Mary M. Niewinski.Advances in Celiac Disease and Gluten-Free Diet[J].Journal of the American Dietetic Association.2008(4)
  • 9K. Alarida,S. Nobile,C. Catassi.Coeliac disease in Libya[J].Digestive and Liver Disease.2006(10)
  • 10Anne Ballinger.Gastroenterology and anaemia[J].Medicine.2006(3)

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