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急性脑卒中与血清N末端B型利钠肽相关性的研究 被引量：3

Correlattion Study of N-terminal Fragment of Brain Natriuretic Peptide and Acute Stroke
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摘要 目的探讨急性脑卒中患者的血清N末端B型利钠肽(NT-pro BNP)的变化,评价血清NT-pro BNP测定的临床意义。方法74例患者分别为急性脑梗死(CI)(42例)和急性脑出血(ICH)组(32例),根据入院时NIHSS评分分为轻度、中度和重度3个亚组,采用ECLIA法检测发病48h内(急性期)及发病第21天(亚急性期)的血清NT-pro BNP水平,与健康对照组进行比较,比较急性期与亚急性期间、各亚组间的血清NT-pro BNP水平差异。结果CI组和ICH组急性期血清NT-pro BNP显著高于对照组(P<0.01),并在亚急性期显著下降(P<0.01);各亚组间急性期血清NT-pro BNP水平均有显著统计学差异(P<0.01)。结论急性期脑卒中患者急性期血清NT-pro BNP水平与病情程度相关。 Objective To observe the changes of N-terminal fragment of brah natriuretic peptide (NT-pro BNP)and in patients with acute stroke. Methods Seventy-four patients with acute stroke were enrolled in the study. Among them, 42 patients with acute ischemic stroke (CI group)and 32 patients with acute intracerebral hemorrhage stroke (ICH group). According to the NIHSS score, acute stroke patients were divided into 3 subgroups. The levels of serum NT-pro BNP were measured within 48 h(acute phase) after onset and at ...
作者 李颖
机构地区 上海市静安区中心医院神经内科
出处 《神经病学与神经康复学杂志》 2009年第3期200-202,共3页 Journal of Neurology and Neurorehabilitation
关键词 脑卒中 B型利钠肽 严重度 acute stroke brain natriuretic peptide severity
分类号 R743.3 [医药卫生—神经病学与精神病学]
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共引文献33039

同被引文献25

  • 1王青,赵林凤.脑钠肽及N末端脑钠肽前体的研究应用进展[J].疾病监测与控制,2011,5(3):187-189. 被引量：1
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神经病学与神经康复学杂志
2009年 第3期

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