摘要
目的分析双侧原发性乳腺癌(bilateral primary breast cancer,BPBC)的临床特点。方法对收治的12例双侧原发性乳腺癌患者的临床资料及预后进行回顾性分析,研究其特点。结果 12例BPBC患者占同期乳腺癌患者(415例)的2.9%,同时性BPBC3例,占0.7%,异时性BPBC9例,占2.2%。91.7%(11/12)的第一侧乳腺癌肿瘤大小为T2,而第二侧乳腺癌中有2例(16.7%)为T0期癌。第一侧乳腺癌病理类型均为浸润性癌,第二侧乳腺癌中有3例(25.0%)为导管内癌。第一侧原发乳腺癌行乳腺癌根治术或改良根治术,第二侧原发乳腺癌有2例行全乳切除术,1例行保乳手术。12例BPBC均无病生存。结论单侧乳腺癌发生后应积极随访,以早期检出对侧病变。BPBC有较早的临床分期和较高的导管内癌比例,可行保乳手术。
Objective To analyze the clinical features of patients with bilateral primary breast cancer (BPBC).Methods We retrospectively analyzed the clinical data of a cohort of 12 patients with BPBC,who were treated during January 1982 and December 2008 in Wuqing Hospital.The clinical features and follow up outcomes were summarized.Results 12 BPBC patients accounted for 2.9% of the total 415 patients who had breast cancer during the period.3 patients (0.7%) were synchronous BPBC,and the other 9 were metachronous BPBC.The diameter of the first primary breast carcinoma was T2 in 11 patients (91.7%),while 2 of the 12 second breast carcinomas were T0(16.7%).The first primary breast carcinomas were all infiltrative carcinomas,and 3 of the 12 second primary breast carcinomas were ductal carcinoma in situ(25.0%).Patients with first primary breast carcinomas underwent radical mastectomy or modified radical mastectomy.And 2 patients with second breast carcinomas received simple mastectomy and 1 patient underwent breast-conserving surgery.Disease-free survival rate of the 12 patients is 100%.Conclusion Surveillance is necessary to screen the contralatera1 breast cancer once the primary breast cancer occurred.The synchronous breast cancer has better features such as earlier stage and higher proportion of DCIS,which make the breast-conserving surgery possible.
出处
《河南外科学杂志》
2010年第5期3-6,共4页
Henan Journal of Surgery
关键词
乳腺肿瘤
双侧
单侧
预后
Breast neoplasms
Bilateral
Unilateral
Prognosis
